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In 1866, Russian scientist Alexander Saytzeff isolated a almost curious and peculiar compound. Information technology was crystalline, scent-less, non-toxic and had a garlic-similar sense of taste when consumed. At the time, Saytzeff had no manner to predict that his discovery was going to evidence highly controversial throughout its unabridged medical history, that it was going to exist tested in thousands of studies and provide miraculous relief for numerous patients.

I'thousand talking here about dimethyl sulfoxide (DMSO), an organic sulfur chemical compound which was used just every bit an industrial solvent, that is, until its medical properties were discovered in 1963 by a inquiry team headed by Stanley W. Jacob, Doc.

DMSO is a by-product of kraft pulping (the 'sulfate process') which converts wood into forest pulp leaving almost pure cellulose fibers. As industrial as information technology may audio, the process merely entails a treatment of woods chips with a mixture of sodium hydroxide and sodium sulfide, known as white liquor, breaking the bonds which link lignin (from the Latin word lignum, pregnant wood) to the cellulose.

DMSO is useful as a hurting reliever and also in burns, acne, arthritis, mental retardation, strokes, amyloidosis, caput injury, scleroderma, it soothes toothaches, eases headaches, hemorroids, muscle strains, it prevents paralysis from spinal-chord injuries and softens scar tissues. In fact, information technology is useful in well over 300 ailments and is safe to use. You lot might think that a compound that has and so many declared uses and benefits should be automatically suspect, so let'due south have a close look at its properties and the data available and we'll shed some light in this miraculous chemical.

Sulfur: The Stuff of Life

DMSO is an intermediate product of the global Sulfur Cycle which distributes bioavailable sulfur for all animal and establish life (Parcell, 2002). Sulfur compounds are establish in all body cells and are indispensable for life, they are needed for a number of chemical reactions involved in the detoxification of drugs and other harmful toxins, and they take potential clinical applications in the handling of a number of conditions such as depression, fibromyalgia, arthritis, interstitial cystitis, athletic injuries, congestive heart failure, diabetes, cancer, and AIDS (Parcell, 2002). Among the sulfur compounds, DMSO is probably the i that has the widest range and greatest number of therapeutic applications ever shown for any other single chemic. It has around 40 pharmacological properties that may be beneficial in the prevention, relief or reversal of numerous diseases (Morton, 1993).

Someone complained to Dr. Jacob of a splitting headache and gave him permission to apply some DMSO later hearing of its capabilities. The headache was gone in minutes, came back in four hours, and left for adept after DMSO was applied a second time. Used for one purpose, sometimes it did another; put on a cold sore, within a few hours it cleared up a woman'due south sinusitis. A adult female who had had a stroke establish later DMSO was painted on her painful jaw that she could now write with her paralyzed manus and could walk ameliorate. (Haley, 2000)

Therapeutic Properties

DMSO is an effective pain killer, blocking nervus conduction fibers that produce hurting. Information technology reduces inflammation and swelling by reducing inflammatory chemicals. It improves claret supply to an area of injury by dilating claret vessels and increasing commitment of oxygen and by reducing blood platelet stickiness. It stimulates healing, which is a key to its usefulness in any condition. It is amidst the almost stiff free radical scavengers known to homo, if non the about strong 1. This is a crucial machinery since some molecules in our bodies produce an unequal number of electrons and the instability of the number causes them to destroy other cells. DMSO hooks on to those molecules and they are then expelled from the body with the DMSO.

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Dr Stanley Jacob working with DMSO in the 1960s

DMSO also penetrates the peel and the blood-brain barrier with ease, penetrating tissues, and entering the bloodstream. Furthermore, DMSO protects the cells from mechanical damage and less of it is needed to attain results every bit fourth dimension passes as oppossed to nearly pharmaceuticals where increasing doses are required. It has a calming effect in the cardinal nervous arrangement and it reaches all areas of the body, when absorbed through the skin, including the brain. That is, DMSO applied to 1 area oft leads to pain relief in some other location due to its systemic upshot.

It acts as a carrier for other substances or drugs and information technology also potentiates their effect. In fact, sure drugs dissolved in DMSO, such as corticoids, antibiotics and insulin, may be used in a lower dose than usual without reducing their therapeutic efficacy and in improver, their undesirable side effects are greatly diminished. Also, drugs are able to laissez passer through the blood-encephalon barrier which is commonly impenetrable.

DMSO promotes the excretion of urine and functions as a muscle relaxant. Information technology boosts the immune system, increasing the production of white cells and macrophages that destroy strange textile and pathogens in the body. It likewise has anti-bacterial, anti-viral and anti-fungal backdrop. DMSO as well increases the permeability of cell membranes, allowing a flushing of toxins from the cell.

DMSO has radioprotective properties confronting lethal and mutagenic furnishings of Ten-rays in cells, cellular systems and whole animals. It also has cryoprotective properties, meaning that it is capable of protecting confronting injury due to freezing.
DMSO has besides been shown to accept cholinesterase properties (Sams, 1967), in other words, information technology inhibits an enzyme from breaking down acetylcholine, increasing both the level and elapsing of action of this of import neurotransmitter. Acetylcholine is responsible for learning and memory and is also calming and relaxing. Acetylcholine is also a major gene in regulating the immune system, interim equally a major brake on inflammation in the trunk.

As a source of sulfur, DMSO aids in heavy metallic detoxification. Sulfur binds with toxic heavy metals (mercury, lead, aluminum, cadmium, arsenic, nickel) and eliminates them via urination, defecation and sweating.

FDA and Big Pharma Obstacles

DMSO is sold in health food stores, mail-club outlets, on the Internet, and in virtually countries around the earth. Information technology is used by millions for its health benefits yet in the U.S., DMSO has FDA blessing only as a preservative of stem cells, bone marrow cells, and organs for transplant, and for interstitial cystitis - a painful inflammatory status of the float which is very hard to treat with other therapies.

That DMSO has not found favor as a remedy for other medical atmospheric condition is partly due to the inability to exam it in double-blind experiments. Blind studies, as the proper noun suggests, requires that a study be done without knowing which patient is taking the placebo or the drug. In the instance of the DMSO, a blind report is incommunicable since the peculiar garlic-similar taste and olfactory property (no thing the route of awarding) gives it away and no satisfactory placebo could be devised that would mimic this particular issue of DMSO (Steinberg, 1967).

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The FDA and 'big pharma' would adopt we remain dependent on their drugs

If you search for DMSO on the U.S. National Library of Medicine (pubmed.gov), you'll get almost 30,000 indexed results, making it one of the most studied compounds of our time. Yet, we are led to believe that DMSO tin't pass the required regulations for its approval in other medical conditions fifty-fifty though its effectiveness and low toxicity contour is unquestionable.

Yous see, DMSO is a common chemic that can be manufactured cheaply. No drug visitor can get an sectional patent since it is also a natural compound, therefore there is no pregnant financial return. In fact, an executive of a major drug company is quoted as saying, "I don't care if DMSO is the major drug of our century and nosotros all know it is, it isn't worth it to u.s.a." [CBS Idiot box bear witness 60 minutes with Mike Wallace, The Riddle of DMSO]. If DMSO were to be approved by the FDA, information technology would be competetive and drug companies would be unable to hold the patents. In the words of the director of the Bureau of Drugs of the FDA, J. Richard Crout, Yard.D., "DMSO is a depression toxicity and safe compound (...) I retrieve that it is a fact of life that drug companies are not going to invest in something unless they call up there is some financial return" [CBS Television set show 60 minutes with Mike Wallace, The Riddle of DMSO].

Despite restrictions on the apply of DMSO, thousands of Americans purchase it on the 'blackness market' each year, its popularity due not to publicity, but rather 'word of rima oris'. When you have something that relieves all kinds of ailments, including some life-threatening ones, people naturally recommend it to friends and family unit!

In Perspective

In the 1960s, research with DMSO on humans was temporarily halted after sure animals treated with DMSO were found to have changes in the eye lens. Some of these changes resembled those seen in aging dogs (Gordon, 1967), simply nevertheless, inquiry was gradually restarted later on no show was plant of eye changes in humans. Equally Daniel Haley reports in his volume Politics in Healing: "Tests in rabbits, dogs, and pigs (merely not humans) had shown some issues. When quantities of DMSO equal to nigh ten times the maximum human dose were given every solar day over a period of six months, slight changes in the lenses of the animals' eyes would result, enough to produce a slight nearsightedness. The lens changes were non enough to crusade dogs difficulty when running - they didn't bump into things - and in some cases, the changes disappeared after the massive DMSO doses were stopped. In no test at that time or since has DMSO ever caused cataracts, either in animals or in humans" (Haley, 2000).

In fact, DMSO is effective for macular degeneration and retinal affliction, both diseases of the heart. This effectiveness was first discovered when patients with retinitis pigmentosa, a retinal disease, were taking DMSO for certain musculoskeleteal disorders. They sensed that their vision had improved and some had remarkable results (Morton, 1993).

Equally far as eyes are concerned, the evidence on DMSO is quite to the contrary. When several patients treated with DMSO for muscular problems reported to Dr. Jacob that their vision had improved, he sent them to Dr. Robert O. Hill, ophthalmologist at the University of Oregon Medical School. Confirming the favorable changes, Dr. Hill began his own experiments with DMSO (after it was known that the lens changes did not happen in humans). His enquiry showed drops of 50% DMSO to be effective in retinitis pigmentosa and macular degeneration, and presented a report on this at the New York Academy of Sciences symposium in 1971. (Haley, 2000)

In dissimilarity, the number of medication-related deaths in the U.S. is estimated at over 200,000 a yr, making medications the 3rd or fourth leading cause of death (Pezzalla, 2005). Fifty-fifty common hurting relievers chosen NSAIDs, examples of which include Advil, Motrin, Aleve and aspirin, account for an estimated 7,600 deaths and 76,000 hospitalizations in the U.S. every twelvemonth (Tamblyn et al, 1997). Taking this into consideration, it is safe to declare that DMSO is amidst the safest substances in the world today. In fact, the classic test for toxicity -the LD-fifty test - measures the lethal dose (LD) at which half of a group of test animals is killed. The LD-50 tests for aspirin and DMSO bear witness that aspirin is seven times more than toxic than DMSO (Haley, 2000).

Quick Guide and Ailments

DMSO is generally applied to the peel in a gel, cream, or liquid. It can be taken past oral fissure or equally an intravenous injection, in many cases along with other drugs. It has also been administered subcutaneously, intramuscularly, intraperitoneally, intrathecally, by inhalation, instilled into the eye, on the mucous membranes, and into the urinary bladder. Strenghs and dosages vary widely.

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If yous are merely dealing with hurting or an injury, employ a topical awarding. Don't drink it. Drinking it is for serious detoxing and other internal necessities. If y'all use a rose scented DMSO cream, chances are that nobody volition be able to smell DMSO's garlic-like smell.

The usual oral dose of DMSO is 1 teaspoon per day of DMSO 70% (Morton, 1993). But since it can trigger detoxification reactions and DMSO's total excretion from the body can accept several days, it is best to do it only once a week. Start with half a teaspoon of DMSO 50% and increase to a teaspoon of DMSO 70% only if any possible detoxification reaction is well tolerated.

When y'all employ liquid DMSO in the skin, let it dry for over 20 to xxx minutes before wiping the remainder out. The pare must exist make clean, dry, and unbroken for any topical use of DMSO. The face and the cervix are more than sensitive to DMSO and no higher concenrations than l% should be applied there. Topical concentrations of DMSO should be kept below seventy% in areas where there is a reduction of circulation. When 60 to ninety% DMSO is applied to the peel, warmth, redness, itching, and somtimes local hives may occur. This unremarkably disappears within a couple of hours and using natural aloe vera, gel or cream, will help counteract or forbid this issue. When 60 to ninety% DMSO is applied to the palm on the hand, the skin may wrinkle and stay that way for several days.

"My brother put some DMSO gel (70% dmso, thirty% aloe vera) on his shoulders and lower part of neck because he had muscle pain/soreness in that surface area, and it caused pare redness/irritation for a few hours, although it did diminish the muscle soreness as well...my grandma has rheumatoid arthritis that made her legs swell upwardly and hurt continuously, and I had her utilise the same DMSO gel, and afterwards nearly ii-3 days of applying it in one case a 24-hour interval, the swelling was 90% gone, and I think inside 4-5 days it was 100% gone, and she said the hurting macerated as well." - Michael Shatskiy, Los Angeles, California, United states of america

Chronic pain patients often have to apply the substance for 6 weeks before a modify occurs, but many report relief to a caste that had not been able to obtain from any other source. In general, the greater the chronicity of the disorder, the longer the handling with DMSO must be employed in order to accomplish palliation (Steinberg , 1967).

Common health problems for which people will apply topical DMSO at habitation include acute musculoskeletal injuries and inflammations. The earlier DMSO is used, the more than dramatic the issue. A 70% concentration of DMSO mixed with water in volumes ranging from 8 to 12 ml, applied on and around the injury in a wide surface area at to the lowest degree iii times daily, will have a healing affect in 4 out ot 5 people.

Arthritis, Sprains, Strains

It provides rapid amelioriation of pain and increased mobility and reduction of inflammation when used topically. Yous can encounter a positive response within 5 to 20 minutes and usually lasting for 4 to 6 hours. (Steinberg, 1967).

"Applying DMSO where information technology injure to a vi-yr-one-time wasted from rheumatoid arthritis, in a half hour the child could motility her shoulder and turn her head for the starting time time in ii years. Persuaded to effort walking, she managed a few steps and so burst into tears. "Why are you crying?" Dr Jacob asked her. "Because it doesn't hurt anymore", she replied. (Haley, 2000)
"My brother has arthritis of the spine. He is in pain and bedridden more than half the time. When he is treated with DMSO, he is able to lead a normal, active life... But one application of this cheap, prophylactic DMSO changed my blood brother from a grimacing patient into an active, pain-complimentary man in exactly 30 minutes!" (Haley, 2000)
June Jones, one time quarterback and later bus of the Atlanta Falcons pro-football team, had a bursitis calcification in his right shoulder. His career almost didn't happen every bit he could hardly lift his arm, let solitary throw a football. Only he was aware of DMSO and had used DMSO for sprains, like thousands of others. He received a shot of DMSO in the shoulder and afterward using DMSO for xxx days direct, the calcification disappeared. (Haley, 2000)

Stroke

Given soon later on a stroke, DMSO can dissolve the clot that causes the stroke, restoring circulation and avoiding paralysis. Once DMSO gets into the torso either daubed on the skin, given in I.V., or by mouth, information technology permeates the body and crosses the brain barrier, so even taken orally it tin ameliorate circulation. Ideally it should be I.V.

Even though DMSO xl% causes a prolongation of bleeding time, it is still indicated for apply in treating embolic or hemorrhagic stroke. DMSO is superior to whatsoever other treatment for wounds to the brain where a great deal of bleeding is present (Morton, 1993).

One man who had a stroke at vii:30 AM refused to go to the hospital until later his wife had spoken with Dr. Stanley Jacob, which didn't happen until 6:30 PM. Starting at vii PM the day of the stroke, she gave him one ounce of 50% DMSO in a lilliputian orange juice every 15 minutes for ii hours and then every one-half hour for 2 hours. The side by side day, her husband was better and soon returned to normal. A substance that tin finish a stroke equally it'south happening is something many might want in their habitation medicine breast .(Haley, 2000)

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Angina, Center Attacks, Injuries of the Brain and Spinal Chord

DMSO may help neutralize harmful effects on the middle and brain in medical disorders involving the caput and spinal chord injury, stroke, memory dysfunction, and ischemic heart disease (Jacob, de la Torre, 2009). A twoscore% DMSO solution should be administered within four hours to be effective, within ninety minutes is best.

Later I.Five. assistants of DMSO, there is an meridian in the corporeality of spinal cord claret flow to the region of trauma. One of the first things that happens later spinal string trauma is that a reduction of oxygen and blood flow sets in, inasmuch every bit the blood vessels constrict or shut downward... Without some treatment, the tissue swells. Eventually, this leads to paralysis. In a cerebral stroke, the fauna volition either become comatose or lethargic or dice. With DMSO infusion immediately after injury (or stroke) all this is prevented. - Dr. Jack de Ia Torre, professor of physiology and neurosurgery at the University of New Mexico
Dr. Stanley Jacob has even given DMSO intravenously to people who were already paralyzed - paraplegics - and some regained use of limbs. Ane human, quadraplegic, recovered enough to go through college then to work in a bank. (Haley, 2000)

Infections

When combined with antibiotics, DMSO will convert leaner which are resistant to a given antibody to beingness sensitive to that aforementioned antibiotic and probably a 80 to 90 per cent solution of DMSO will be required in guild to be clinically useful ( Pottz, Rampey, Benjamin,1967). DMSO has been used to send antibiotics to hard-to-attain areas of the body with excellent results, such equally the bone marrow and brain (Sanders, 1967).

DMSO tin dissolve a virus poly peptide coating, leaving the virus cadre unprotected with its nucleic acid exposed to the immune system. Applied topically, information technology alleviates the lesions that occur as a event of Herpes Zoster, shingles (Morton, 1993).
Placed into the nostrils or topically in the face, DMSO can open blocked sinuses within a few minutes and information technology has been used with sucess in patients with polyps (Marvin, 1967).

DMSO can clear up mucilage disease and reduce tooth decay and their hurting by painting information technology on the involved areas.

"I have some pharmaceutical class DMSO and I cascade about two teaspoons in a drinking glass in the evening, put my 20 mg of doxycycline in it, add together about 2 teaspoons of distilled h2o, and then swish it effectually in my mouth for about 2 or 3 minutes so swallow information technology. And then I guess information technology is most 50% solution. It'due south actually working on my mouth. That inflamed area of my jaw has calmed downwardly nigh 70% in just a couple of days. Or more than, actually. I look it to be completely soothed by tomorrow later on tonight's dose of DMSO." - L., Toulouse, France

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Several books have been published on the benefits of DMSO

Keloids, Scars, Burns, Bruises

A concentration of 50 to 80% put on two or three times a day will flatten a raised scar subsequently several months. It is of considerable value in superficial burns (Goldman, 1967) and when applied quickly to an injury, it can eliminate any bruising.

"I accept been applying it to my face for two weeks... I had a bout of acne in March, and this healed the harm pretty well just what amazed me is that my hyperpigmentation (melasma) has also faded very noticeably. In fact, it's astonishing!" - HG, United States
"I diluted a 50% solution and practical it topically to the inflamed lymph node. I applied it again this evening. I am totally amazed! In that location is a noticeable decrease in the size of the node, in merely ii applications! And it no longer feels matted. This node has been bloated for over 20 years!!! - Melissa Medlock, Coldwater, Michigan, USA

Podiatry

DMSO can be effective in the treatment of painful corns, calluses, ingrown toenails, bunions, hammertoes, heel spurs, and the inflammation of gouty big toes.
Varicose veins and thrombophlebitis

Topical DMSO tin can whiten telangiectasias, small dilated blood vessels most the surface of the skin. Information technology can as well decrease the size of varicosities in the legs and the inflammation that goes with it, along with a relief of their cramping discomfort (Marvin, 1967. Blumenthal, Fuchs, 1967).

Eye problems

I drib of a 25% DMSO solution (diluted in sterile physiologic or saline solution) once or twice per day is useful for middle issues, including cataracts or glaucoma.

"DMSO is astonishing, I've besides read various good results with using it in the eyes. Being the adventurous type myself, today I diluted DMSO down to thirty% and put 2 drops in one of my eyes that has been having red spots effectually the iris. The scarlet spots diminished drastically. The simply side event was a slight burning sensation, similar to those drops you get when one goes for a glaucoma test, without the side event of dilated pupils." - DZ, United States

Headaches

DMSO is highly effective in vascular headaches and in muscular tension which and so ofttimes goes with headaches. It may be used on hairy areas such as the scalp and it also may be used near the eyes. A 90% solution is more than constructive (Ogden, 1967).

Mental Disorders

DMSO has been useful in the treatment of patients with the post-obit diagnoses: (1) overexcited states (acute schizophrenic reactions, manic phase of the manic-depressive psychoses, alcoholic psychoses, symptomatic psychoses); (2) some symptoms of the chronic psychoses (autism, stereotypia, negativism, abnormal behavior or delusional states) ; (3) severe neuroses (anxiety reactions, obsessives)( Ramírez, Luza, 1967).

McGrady called special attention to an extraordinary newspaper presented past Dr. Eduardo Ramirez and Dr. Segisfredo Luza of the Ayetano Heredia Academy in Lima, Peru. After extensive tests on animals and so on normal humans, Dr. Ramirez reported "injecting fifty% or lxxx% DMSO intramuscularly into patients with astute and chronic schizophrenia" and that "of the 14 astute cases, every single i was discharged from the infirmary within 45 days after the start of DMSO treatment... He said that iv of the xi chronic cases, one of whom has been sick for 14 years, were discharged eventually, and the other 7 improved a great deal and were given occupational therapy... He observed rapid decrease in agitation... recession of persecution feeling, a relatively sudden trend to communicate and to stay clean.., the wane of obsessions, return to alertness, and a calmness where there had been restlessness and feet". (Haley, 2000)

Genitourinary disorders

DMSO has been used in the treatment of a number of patients with various genitourinary disorders, including Peyronie's disease, interstitial cystitis, acute epididymitis. Some have obtained dramatic and gratifying relief of symptoms (Persky, Steeart, 1967).

Miscellaneous

DMSO in conjunction with other treatments has shown to regress cancer in a very effective way (Ayre, 1967).

Intravenous administration of DMSO markedly reduces pathological abdominal permeability while preserving the gut's assimilation capacities (Wang et al, 1996). Because that gut permeability ('leaky gut') has a fundamental role in chronic degenerative diseases, this is of smashing clinical importance.

DMSO also has splendid results in the skin of people affected with scleroderma, results which have never been observed with any other method of therapy (Scherbel et al, 1967).

Mrs. Jean Puccio of Washington, DC testified at hearings of Senator Edward Kennedy's sub-commission on wellness in 1980 on her recovery from scleroderma. Diagnosed in 1971, she was told that no medication would assistance, and that she would probably soon confront a wheelchair and early death. By the time she found Dr. Jacob (through discussion of mouth), she told the Senators, "I was having difficulty animate, walking, and eating". The affliction "thickens the tissue and makes your peel so tight you cannot move. Information technology was difficult for me to drive, to turn the ignition in my auto or turn my body". Her dentist could not work on her for awhile considering she could not open her oral fissure. "Now I can open my oral cavity like anybody", she said. After her sensitized skin burned from topical awarding of DMSO, Dr. Jacob suggested taking it orally. "Within vi months", she testified, "my condition reversed almost immediately. I can practice anything everyone else tin can do now" (Haley, 2000).

Hopefully, this brief overview of DMSO'due south smashing capabilities has helped to illustrate how it is indeed, the cure of our times. I'm convinced of its therapeutic ability, both by my own feel and that one of scores of people, non to mention the back-upwardly of published scientific literature. Its uses and applications make it a very handy compound to accept on your medical shelf. In pure grade, the life of DMSO is indefinite, so it may be used for years.

Troubleshooting

The garlic-like body odor and taste in the mouth that some experience is attributable to a specific DMSO metabolite: dimethyl sulfide (DMS), a component of natural onion and garlic flavors (McKim, Strub, 2008). This can concluding for i or two days and in a pocket-size number of people, especially men, the odour can be very pungent. Drinking enough h2o will help diffuse the smell. Other side effects - such as breadbasket upset, headaches, dizziness, and sedation - are very likely related to detoxification reactions prompted by the DMSO.

Only purified and properly diluted DMSO should be used. When y'all dilute a pure DMSO solution, always exercise it in distilled water. When it is applied, the pare site as well equally the applying hand should be thoroughly cleaned before application. This is of utmost importance as DMSO's properties allow contaminants to be absorbed through the peel and transported into the bloodstream.

DMSO is known to be one of the least toxic substances in biology (Parcell, 2002), so whatsoever serious side furnishings should come from potential contaminants or the intake of concomintant drugs that DMSO will carry into the body. Worth repeating again, DMSO and any substance dissolved in it, volition penetrate the skin, the blood-brain bulwark, and other parts of the body very fast.

Call back also that DMSO increases the effects of drugs like blood thinners, steroids, middle medicines, sedatives, etc. In addition to that, acetone or acid contamination of DMSO can lead to serious medical consequences. Be aware of this trouble when ownership unreliable DMSO. A pure DMSO solution will turn solid (like water ice) in the refigerator within two hours. If, when the frozen bottle is turned upside down, fiddling rivulets of water flow through the water ice, you probably possess the veterinary grade DMSO. This is a 90% concentration. X percent is distilled water (Morton, 1993).

Women are discouraged from using DMSO during pregnancy or breastfeeding, even though DMSO is used to preserve frozen homo embryos. DMSO can interfere with liver function tests and give a simulated reading. That problem is easily solved by waiting a week subsequently DMSO usage before taking the examination.

Long-term use has been documented as safe. Center damage, reported in laboratory animals, has non been confirmed. Side effects such as skin rash and itching after topical application, breaking up of claret elements afterward intravenous infusion, can be avoided in large function by employing more dilute solutions. Despite these side effects, DMSO is used equally a preservative for blood elements and stalk cells (McKim, Strub, 2008).

When DMSO is diluted with water, estrus is released. The canteen volition be warm to the touch. This is a temporary, harmless reaction.

Since DMSO causes dryness and scaling of the outer layer of the skin, skin diseases characterized by scaling (psoriasis) could exist aggravated by the use of DMSO. But DMSO applied topically for only a few days has been useful in psoriasis. Prolonged use of DMSO for the handling of psoriasis is not advised nevertheless, as it tin can worsen the psoriatic condition (Engel, 1967), only DMSO taken orally is suggested.

"I'm happy to say that taking DMSO in conjunction with implementing the detoxification suggestions that were given is starting to take care of many of my remaining psoriasis issues. A couple areas are still being stubborn, only I've noticed a lot of general improvement. Using DMSO topically also helped amend a patch of eczema that my wife has been bothered by for quite a while." - Peter Norquest, Tucson, Arizona, United States

DMSO2, a derivative of DMSO, is amend tolerated and doesn't have the olfactory property and irritation side effects. Despite this positive attribute, it hasn't surpassed the effectiveness, fascination and popularity of DMSO. Information technology is besides known every bit methylsufonlmethane or MSM, an unabridged topic for some other article by itself!

Sulfur is an element of the world and it is essential to life, it every bit amid the most prevalent elemenents in the human being trunk. Allergic reactions to sulfur are not possible because sulfur has no protein component. When people are 'allergic to sulfur', what they actually hateful is that they are allergic or sensitive mainly to sure sulfur-containing drugs or proteins, most notably sulfa antibiotics (sulfonamides) or to sulfites (preservatives used in wines and some foods), or to foods with a high sulfur content (broccoli, cauliflower, garlic, onions, etc). Many individuals with allergies to sulfa drugs, sulfites, or high sulfur containing foods (similar the author) do non experience problems taking DMSO, considering apart from sulfur, DMSO bears no relation to these substances.

As always, proceed with caution, do your homework, and consult a wellness care provider in example of doubts.

References:

Ayre JE, LeGuerrier J. Some (regressive) effects of DMSO dexamethasone upon cervical cells in cervical dysplasia and carcinoma in situ. Ann Northward Y Acad Sci. 1967 Mar fifteen;141(one):414-22.

Blumenthal LS, Fuchs G. The clinical use of dimethyl sulfoxide on diverse headaches, musculoskeletal, and other general medical disorders. Ann Due north Y Acad Sci. 1967 Mar 15;141(ane):572-85.

Engel MF. Indications and contraindications for the utilise of DMSO in clinical dermatology. Ann N Y Acad Sci. 1967 Mar 15;141(one):638-45.

Goldman J. A brief resume of clinical observations in the treatment of superficial burns, trigeminal neuralgia, acute bursitis, and acute musculo-skeletal trauma with dimethyl sulfoxide. Ann N Y Acad Sci. 1967 Mar 15;141(1):653-iv.

Gordon DM. Dimethyl sulfoxide in ophthalmology, with especial reference to possible toxic effects. Ann North Y Acad Sci. 1967 Mar xv;141(one):392-401.

Haley Daniel. Politics in Healing. Potomac Valley Press, 2000.

Jacob SW, de la Torre JC. Pharmacology of dimethyl sulfoxide in cardiac and CNS impairment. Pharmacol Rep. 2009 Mar-April;61(2):225-35.

Marvin P. Interval therapy with Dimethyl Sulfoxide. Register of the New York University of Sciences. Volume 141, Biological Actions of Dimethyl Sulfoxide pages 551 - 554.

McKim A.Southward., Strub Robert. Dimethyl Sulfoxide USP, PhEur in Approved Pharmaceutical Products and Medical Devices. Pharmaceutical Technology, May 2008.

Ogden HD. Experiences with DMSO in treatment of headache. Ann N Y Acad Sci. 1967 Mar 15;141(1):646-8.

Parcell S. Sulfur in human being diet and applications in medicine. Altern Med Rev. 2002 Feb;7(ane):22-44.

Persky L, Steeart BH. The use of dimethyl sulfoxide in the treatment of genitourinary disorders. Ann N Y Acad Sci. 1967 Mar fifteen;141(1):551-4.

Pezalla Due east. Preventing adverse drug reactions in the general population. Manag Intendance Interface. 2005 October;xviii(10):49-52.

Pottz GE, Rampey JH, Benjamin F.Ann- The event of dimethyl sulfoxide (DMSO) on antibiotic sensitivity of a grouping of medically important microorganisms: preliminary written report. Ann N Y Acad Sci. 1967 Mar 15;141(1):261-72.

Ramírez E, Luza S. Dimethyl sulfoxide in the handling of mental patients. Ann Northward Y Acad Sci. 1967 Mar 15;141(1):655-67.

Sams WM Jr. The effects of dimethyl sulfoxide on nervus conduction. Ann N Y Acad Sci. 1967 Mar 15;141(1):242-7.

Sanders M. Discussion. Annals of the New York Academy of Sciences. Volume 141, Biological Actions of Dimethyl Sulfoxide pages 649 - 652, March 1967.

Scherbel AL, McCormack LJ, Layle JK. Farther observations on the effect of dimethyl sulfoxide in patients with generalized scleroderma. (Progressive systemic sclerosis). Ann N Y Acad Sci. 1967 Mar fifteen;141(1):613-29.

Steinberg A. The employment of dimethyl sulfoxide as an antiinflammatory agent and steroid-transporter in diversified clinical diseases. Ann N Y Acad Sci. 1967 Mar fifteen;141(i):532-50.

Tamblyn R, Berkson Fifty, Dauphinee WD, Gayton D, Grad R, Huang A, Isaac L, McLeod P, Snell L. Unnecessary prescribing of NSAIDs and the management of NSAID-related gastropathy in medical practice. Ann Intern Med. 1997 Sep 15;127(6):429-38.

Walker Morton. DMSO Nature's Healer. New York: Avery, 1993.

Wang XD, Wang Q, Andersson R, Ihse I. Alterations in intestinal function in acute pancreatitis in an experimental model. Br J Surg. 1996 Nov;83(11):1537-43.

Well-nigh the author:
Gabriela Segura M.D. is a eye surgeon with all-encompassing experience and interest in alternative health reasearch, psychology and the man condition. She is a regular contributor to Sott.internet and maintains her health website Health Matrix